Neuropilin-1 aggravates liver cirrhosis by promoting angiogenesis via VEGFR2-dependent PI3K/Akt pathway in hepatic sinusoidal endothelial cells

BACKGROUND: We have revealed that neuropilin-1 (NRP-1) promoted hepatic stellate cell activation and liver fibrosis through its profibrogenic signalling pathways. However, the role of NRP-1 in angiogenesis in hepatic sinusoidal endothelial cells (HSECs) during liver cirrhosis remains unclear. METHOD...

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Detalles Bibliográficos
Autores principales: Wang, Le, Feng, Yuemin, Xie, Xiaoyu, Wu, Hao, Su, Xiao Nan, Qi, Jianni, Xin, Wei, Gao, Lifen, Zhang, Ying, Shah, Vijay H., Zhu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558257/
https://www.ncbi.nlm.nih.gov/pubmed/31060904
http://dx.doi.org/10.1016/j.ebiom.2019.04.050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558257/
https://www.ncbi.nlm.nih.gov/pubmed/31060904
http://dx.doi.org/10.1016/j.ebiom.2019.04.050

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