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Human gingival tissue-derived MSC suppress osteoclastogenesis and bone erosion via CD39-adenosine signal pathway in autoimmune arthritis

BACKGROUND: Bone destruction is one of many severe complications that occurs in patients with rheumatoid arthritis (RA) and current therapies are unable to cure this manifestation. This study here aims to determine whether GMSC can directly inhibit osteoclast formation and eventually attenuate osteo...

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Detalles Bibliográficos
Autores principales: Luo, Yang, Wu, Wenbin, Gu, Jian, Zhang, Ximei, Dang, Junlong, Wang, Julie, Zheng, Yongjiang, Huang, Feng, Yuan, Jia, Xue, Youqiu, Fu, Qingling, Kandalam, Umadevi, Colello, Jacob, Zheng, Song Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558261/
https://www.ncbi.nlm.nih.gov/pubmed/31076346
http://dx.doi.org/10.1016/j.ebiom.2019.04.058