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Human gingival tissue-derived MSC suppress osteoclastogenesis and bone erosion via CD39-adenosine signal pathway in autoimmune arthritis
BACKGROUND: Bone destruction is one of many severe complications that occurs in patients with rheumatoid arthritis (RA) and current therapies are unable to cure this manifestation. This study here aims to determine whether GMSC can directly inhibit osteoclast formation and eventually attenuate osteo...
Autores principales: | Luo, Yang, Wu, Wenbin, Gu, Jian, Zhang, Ximei, Dang, Junlong, Wang, Julie, Zheng, Yongjiang, Huang, Feng, Yuan, Jia, Xue, Youqiu, Fu, Qingling, Kandalam, Umadevi, Colello, Jacob, Zheng, Song Guo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558261/ https://www.ncbi.nlm.nih.gov/pubmed/31076346 http://dx.doi.org/10.1016/j.ebiom.2019.04.058 |
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