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Preclinical Absorption, Distribution, Metabolism, and Excretion of Sodium Danshensu, One of the Main Water-Soluble Ingredients in Salvia miltiorrhiza, in Rats

In this study, the absorption, distribution, metabolism and excretion (ADME) of sodium danshensu (Sodium DL-β-(3, 4-dihydroxyphenyl)lactate), one of the main water-soluble active constituents in Salvia miltiorrhiza, were evaluated in rats. Pharmacokinetic study was evaluated in doses of 15, 30, and...

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Detalles Bibliográficos
Autores principales: Meng, Xiangguo, Jiang, Jingjing, Pan, Hui, Wu, Shengyuan, Wang, Shuowen, Lou, Yuefen, Fan, Guorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558371/
https://www.ncbi.nlm.nih.gov/pubmed/31231211
http://dx.doi.org/10.3389/fphar.2019.00554