Cell of Origin and Genetic Alterations in the Pathogenesis of Multiple Myeloma

B cell activation and differentiation yields plasma cells with high affinity antibodies to a given antigen in a time-frame that allows for host protection. Although the end product is most commonly humoral immunity, the rapid proliferation and somatic mutation of the B cell receptor also results in...

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Detalles Bibliográficos
Autores principales: Barwick, Benjamin G., Gupta, Vikas A., Vertino, Paula M., Boise, Lawrence H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558388/
https://www.ncbi.nlm.nih.gov/pubmed/31231360
http://dx.doi.org/10.3389/fimmu.2019.01121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558388/
https://www.ncbi.nlm.nih.gov/pubmed/31231360
http://dx.doi.org/10.3389/fimmu.2019.01121

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