Downregulation of Transcription Factor T-Bet as a Protective Strategy in Monosodium Urate-Induced Gouty Inflammation

Gout is sterile joint inflammation triggered by the damaging effects of monosodium urate (MSU) crystals accumulation. Previous studies suggest transcription factor T-bet plays an important role in inflammatory arthritis. Notably, mice lacking T-bet markedly reduced joint inflammation of rheumatoid a...

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Detalles Bibliográficos
Autores principales: Yang, Qi-Bin, He, Yong-Long, Zhang, Quan-Bo, Mi, Qing-Sheng, Zhou, Jing-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558421/
https://www.ncbi.nlm.nih.gov/pubmed/31231373
http://dx.doi.org/10.3389/fimmu.2019.01199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558421/
https://www.ncbi.nlm.nih.gov/pubmed/31231373
http://dx.doi.org/10.3389/fimmu.2019.01199

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