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Syncytin 1, CD9, and CD47 regulating cell fusion to form PGCCs associated with cAMP/PKA and JNK signaling pathway

BACKGROUND: We have previously reported the formation of polyploid giant cancer cells (PGCCs) through endoreduplication or cell fusion after cobalt chloride (CoCl(2)) induction. Cell fusion plays an important role in development and disease. However, the underlying molecular mechanism concerning cel...

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Detalles Bibliográficos
Autores principales: Fei, Fei, Li, Chunyuan, Wang, Xinlu, Du, Jiaxing, Liu, Kai, Li, Bo, Yao, Peiyu, Li, Yuwei, Zhang, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558479/
https://www.ncbi.nlm.nih.gov/pubmed/31025548
http://dx.doi.org/10.1002/cam4.2173