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Genetic Deletion of GABA(A) Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development

In the adult brain GABA(A) receptors (GABA(A)Rs) mediate the majority of synaptic inhibition that provides inhibitory balance to excitatory drive and controls neuronal output. In the immature brain GABA(A)R signaling is critical for neuronal development. However, the cell-autonomous role of GABA(A)R...

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Detalles Bibliográficos
Autores principales: Duan, Jingjing, Pandey, Saurabh, Li, Tianming, Castellano, David, Gu, Xinglong, Li, Jun, Tian, Qingjun, Lu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558517/
https://www.ncbi.nlm.nih.gov/pubmed/31231192
http://dx.doi.org/10.3389/fncel.2019.00217