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Active Vitamin D and Vitamin D Receptor Help Prevent High Glucose Induced Oxidative Stress of Renal Tubular Cells via AKT/UCP2 Signaling Pathway

BACKGROUND: It has been documented that vitamin D supplementation showed an improvement of symptoms of diabetic nephropathy; however, the underlying mechanisms remain unknown. We here tested the hypothesis that active vitamin D is able to up-regulate AKT/UCP2 signaling to alleviate oxidative stress...

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Detalles Bibliográficos
Autores principales: Zhu, XiaoJuan, Wu, ShengHua, Guo, HanCheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558621/
https://www.ncbi.nlm.nih.gov/pubmed/31275989
http://dx.doi.org/10.1155/2019/9013904