Cargando…

Expression of immune checkpoint receptors Indoleamine 2,3‐dioxygenase and T cell Ig and ITIM domain in metastatic versus nonmetastatic choroidal melanoma

BACKGROUND: Survival in metastasized cutaneous melanoma (CM) has been improved with the advent of inhibitors of immune checkpoints CTLA4 and PD‐1. In contrast, the response rate for inhibition of these checkpoints in uveal melanoma (UM) is very low. Other checkpoints including IDO and TIGIT may be t...

Descripción completa

Detalles Bibliográficos
Autores principales: Stålhammar, Gustav, Seregard, Stefan, Grossniklaus, Hans E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558646/
https://www.ncbi.nlm.nih.gov/pubmed/30993893
http://dx.doi.org/10.1002/cam4.2167