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An improved nucleic acid extraction method from dried blood spots for amplification of Plasmodium falciparum kelch13 for detection of artemisinin resistance

BACKGROUND: Mutational analysis of the Plasmodium falciparum kelch 13 (k13) gene is routinely performed to track the emergence and spread of artemisinin resistance. Surveillance of resistance markers has been impeded by the difficulty of extracting sufficient DNA from low parasite density infections...

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Detalles Bibliográficos
Autores principales: Zainabadi, Kayvan, Nyunt, Myaing M., Plowe, Christopher V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558694/
https://www.ncbi.nlm.nih.gov/pubmed/31185976
http://dx.doi.org/10.1186/s12936-019-2817-8