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Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification

BACKGROUND: Published genetic risk scores for breast cancer (BC) so far have been based on a relatively small number of markers and are not necessarily using the full potential of large-scale Genome-Wide Association Studies. This study aimed to identify an efficient polygenic predictor for BC based...

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Detalles Bibliográficos
Autores principales: Läll, Kristi, Lepamets, Maarja, Palover, Marili, Esko, Tõnu, Metspalu, Andres, Tõnisson, Neeme, Padrik, Peeter, Mägi, Reedik, Fischer, Krista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558751/
https://www.ncbi.nlm.nih.gov/pubmed/31182048
http://dx.doi.org/10.1186/s12885-019-5783-1