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Inhibiting eukaryotic ribosome biogenesis

BACKGROUND: Ribosome biogenesis is a central process in every growing cell. In eukaryotes, it requires more than 250 non-ribosomal assembly factors, most of which are essential. Despite this large repertoire of potential targets, only very few chemical inhibitors of ribosome biogenesis are known so...

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Detalles Bibliográficos
Autores principales: Awad, Dominik, Prattes, Michael, Kofler, Lisa, Rössler, Ingrid, Loibl, Mathias, Pertl, Melanie, Zisser, Gertrude, Wolinski, Heimo, Pertschy, Brigitte, Bergler, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558755/
https://www.ncbi.nlm.nih.gov/pubmed/31182083
http://dx.doi.org/10.1186/s12915-019-0664-2