Comprehensive genomic characterization of breast tumors with BRCA1 and BRCA2 mutations

BACKGROUND: Germline mutations in the BRCA1 and BRCA2 genes predispose carriers to breast and ovarian cancer, and there remains a need to identify the specific genomic mechanisms by which cancer evolves in these patients. Here we present a systematic genomic analysis of breast tumors with BRCA1 and...

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Detalles Bibliográficos
Autores principales: Lal, Avantika, Ramazzotti, Daniele, Weng, Ziming, Liu, Keli, Ford, James M., Sidow, Arend
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558765/
https://www.ncbi.nlm.nih.gov/pubmed/31182087
http://dx.doi.org/10.1186/s12920-019-0545-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558765/
https://www.ncbi.nlm.nih.gov/pubmed/31182087
http://dx.doi.org/10.1186/s12920-019-0545-0

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