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Smoking-associated AHRR demethylation in cord blood DNA: impact of CD235a+ nucleated red blood cells

BACKGROUND: Numerous studies have demonstrated that DNA methylation levels in the aryl hydrocarbon receptor repressor (AHRR) gene measured in cord blood are significantly associated with prenatal tobacco smoke exposure and can be used as a fetal exposure biomarker. The mechanism driving this demethy...

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Detalles Bibliográficos
Autores principales: Bergens, Matthew A., Pittman, Gary S., Thompson, Isabel J. B., Campbell, Michelle R., Wang, Xuting, Hoyo, Cathrine, Bell, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558773/
https://www.ncbi.nlm.nih.gov/pubmed/31182156
http://dx.doi.org/10.1186/s13148-019-0686-1