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The activin-follistatin anti-inflammatory cycle is deregulated in synovial fibroblasts

BACKGROUND: Activin A and follistatin exhibit immunomodulatory functions, thus affecting autoinflammatory processes as found in rheumatoid arthritis (RA). The impact of both proteins on the behavior of synovial fibroblasts (SF) in RA as well as in osteoarthritis (OA) is unknown. METHODS: Immunohisto...

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Detalles Bibliográficos
Autores principales: Diller, Magnus, Frommer, Klaus, Dankbar, Berno, Tarner, Ingo, Hülser, Marie-Lisa, Tsiklauri, Lali, Hasseli, Rebecca, Sauerbier, Michael, Pap, Thomas, Rehart, Stefan, Müller-Ladner, Ulf, Neumann, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558802/
https://www.ncbi.nlm.nih.gov/pubmed/31182152
http://dx.doi.org/10.1186/s13075-019-1926-7