Oridonin protects LPS-induced acute lung injury by modulating Nrf2-mediated oxidative stress and Nrf2-independent NLRP3 and NF-κB pathways

BACKGROUND: Oxidative stress and the resulting inflammation are essential pathological processes in acute lung injury (ALI). Nuclear factor erythroid 2-related factor 2 (Nrf2), a vital transcriptional factor, possesses antioxidative potential and has become a primary target to treat many diseases. O...

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Detalles Bibliográficos
Autores principales: Yang, Huahong, Lv, Hongming, Li, Haijun, Ci, Xinxin, Peng, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558832/
https://www.ncbi.nlm.nih.gov/pubmed/31186013
http://dx.doi.org/10.1186/s12964-019-0366-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558832/
https://www.ncbi.nlm.nih.gov/pubmed/31186013
http://dx.doi.org/10.1186/s12964-019-0366-y

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