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Oridonin protects LPS-induced acute lung injury by modulating Nrf2-mediated oxidative stress and Nrf2-independent NLRP3 and NF-κB pathways

BACKGROUND: Oxidative stress and the resulting inflammation are essential pathological processes in acute lung injury (ALI). Nuclear factor erythroid 2-related factor 2 (Nrf2), a vital transcriptional factor, possesses antioxidative potential and has become a primary target to treat many diseases. O...

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Detalles Bibliográficos
Autores principales:	Yang, Huahong, Lv, Hongming, Li, Haijun, Ci, Xinxin, Peng, Liping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558832/ https://www.ncbi.nlm.nih.gov/pubmed/31186013 http://dx.doi.org/10.1186/s12964-019-0366-y

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