Confounding of linkage disequilibrium patterns in large scale DNA based gene-gene interaction studies

BACKGROUND: In Genome-Wide Association Studies (GWAS), the concept of linkage disequilibrium is important as it allows identifying genetic markers that tag the actual causal variants. In Genome-Wide Association Interaction Studies (GWAIS), similar principles hold for pairs of causal variants. Howeve...

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Detalles Bibliográficos
Autores principales: Joiret, Marc, Mahachie John, Jestinah M., Gusareva, Elena S., Van Steen, Kristel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558841/
https://www.ncbi.nlm.nih.gov/pubmed/31198442
http://dx.doi.org/10.1186/s13040-019-0199-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558841/
https://www.ncbi.nlm.nih.gov/pubmed/31198442
http://dx.doi.org/10.1186/s13040-019-0199-7

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