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Protein-protein interaction prediction using a hybrid feature representation and a stacked generalization scheme

BACKGROUND: Although various machine learning-based predictors have been developed for estimating protein–protein interactions, their performances vary with dataset and species, and are affected by two primary aspects: choice of learning algorithm, and the representation of protein pairs. To improve...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Hsi, Wang, Tsai-Feng, Hu, Yuh-Jyh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558856/
https://www.ncbi.nlm.nih.gov/pubmed/31182027
http://dx.doi.org/10.1186/s12859-019-2907-1