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Panax notoginseng saponins promote liver regeneration through activation of the PI3K/AKT/mTOR cell proliferation pathway and upregulation of the AKT/Bad cell survival pathway in mice

BACKGROUD: The regenerative capacity of the liver is crucial for the host to survive after serious hepatic injuries, tumor resection, or living donor liver transplantation. Panax notoginseng saponins (PNS) have been reported to exert protective effects during organ injuries. The present study aimed...

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Detalles Bibliográficos
Autores principales: Zhong, Hua, Wu, Hao, Bai, He, Wang, Menghao, Wen, Jian, Gong, Jianping, Miao, Mingyong, Yuan, Fangchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558887/
https://www.ncbi.nlm.nih.gov/pubmed/31182089
http://dx.doi.org/10.1186/s12906-019-2536-2