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Neuronal Lamin regulates motor circuit integrity and controls motor function and lifespan

Neuronal aging involves a progressive decline in cognitive abilities and loss of motor function. Mutations in human Lamin genes (LMNA, LMNB1, LMNB2) lead to a wide-range of diseases including muscular dystrophy, peripheral neuropathy and progeria. Here we investigate the role of neuronal Lamin in re...

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Detalles Bibliográficos
Autores principales: Oyston, Lisa J., Lin, Yong Qi, Khuong, Thang M., Wang, Qiao-Ping, Lau, Man Tat, Clark, Teleri, Neely, G. Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558924/
https://www.ncbi.nlm.nih.gov/pubmed/31225490
http://dx.doi.org/10.15698/cst2018.09.152