SKP2 and OTUD1 govern non-proteolytic ubiquitination of YAP that promotes YAP nuclear localization and activity

Dysregulation of signaling pathways that control organ size, such as the AKT-mTOR and Hippo-YAP pathways, often leads to tumorigenesis and metastasis. The Hippo pathway effector YAP is a transcriptional co-activator overexpressed or activated in human tumors. Accumulating evidence has demonstrated t...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Fan, Xiao, Zhenna, Sun, Yutong, Ma, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Microreview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558927/
https://www.ncbi.nlm.nih.gov/pubmed/31225491
http://dx.doi.org/10.15698/cst2018.09.153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558927/
https://www.ncbi.nlm.nih.gov/pubmed/31225491
http://dx.doi.org/10.15698/cst2018.09.153

Ejemplares similares