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Celastrol Enhances the Anti-Liver Cancer Activity of Sorafenib

BACKGROUND: Sorafenib, a multiple-target-point kinase inhibitor, has been used as a standard treatment for advanced liver cancer and has shown therapeutic benefits. However, resistance often occurs, prompting the need for identification of synergizing agents. Celastrol is a major active ingredient o...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Chen, Zhi, Wu, Shu-Sheng, Xu, Jun, Kong, Ling-Chun, Wei, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559000/
https://www.ncbi.nlm.nih.gov/pubmed/31152143
http://dx.doi.org/10.12659/MSM.914060