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Sirt1 inhibits HG-induced endothelial injury: Role of Mff-based mitochondrial fission and F-actin homeostasis-mediated cellular migration

Although sirtuin 1 (Sirt1) has been found to be involved in diabetic vasculopathy and high glucose (HG)-mediated endothelial injury, the underlying mechanisms remain to be fully elucidated. The aim of the present study was to investigate the role of Sirt1 in HG-induced endothelial injury and its pot...

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Detalles Bibliográficos
Autores principales: Qin, Ruijie, Zhang, Lina, Lin, Dong, Xiao, Fei, Guo, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559301/
https://www.ncbi.nlm.nih.gov/pubmed/31115479
http://dx.doi.org/10.3892/ijmm.2019.4185