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Aminosalicylic acid reduces ER stress and Schwann cell death induced by MPZ mutations
Mutations in myelin protein zero (MPZ) cause inherited peripheral neuropathies, including Charcot-Marie-Tooth disease (CMT) and Dejerine-Sottas neuropathy. Mutant MPZ proteins have previously been reported to cause CMT via enhanced endoplasmic reticulum (ER) stress and Schwann cell (SC) death, altho...
Autores principales: | Chang, Eun Hyuk, Mo, Won Min, Doo, Hyun Myung, Lee, Ji-Su, Park, Hwan Tae, Choi, Byung-Ok, Hong, Young Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559330/ https://www.ncbi.nlm.nih.gov/pubmed/31059078 http://dx.doi.org/10.3892/ijmm.2019.4178 |
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