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NMDA receptor activation inhibits the protective effect of BM-MSCs on bleomycin-induced lung epithelial cell damage by inhibiting ERK signaling and the paracrine factor HGF

Endoplasmic reticulum (ER) stress in alveolar epithelial cells (AECs) is associated with the pathogenesis of pulmonary fibrosis. Bone marrow-derived mesenchymal stromal cells (BM-MSCs) can exert protective effects on ER-stressed AECs via paracrine signaling. In the present study, mouse lung epitheli...

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Detalles Bibliográficos
Autores principales: Peng, Xiangping, Li, Xiaohong, Li, Chen, Yue, Shaojie, Huang, Yanhong, Huang, Pu, Cheng, Haipeng, Zhou, Yan, Tang, Yiting, Liu, Wei, Feng, Dandan, Luo, Ziqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559344/
https://www.ncbi.nlm.nih.gov/pubmed/31115492
http://dx.doi.org/10.3892/ijmm.2019.4195