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Simulation of single-protein nanopore sensing shows feasibility for whole-proteome identification

Single-molecule techniques for protein sequencing are making headway towards single-cell proteomics and are projected to propel our understanding of cellular biology and disease. Yet, single cell proteomics presents a substantial unmet challenge due to the unavailability of protein amplification tec...

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Detalles Bibliográficos
Autores principales: Ohayon, Shilo, Girsault, Arik, Nasser, Maisa, Shen-Orr, Shai, Meller, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559672/
https://www.ncbi.nlm.nih.gov/pubmed/31145734
http://dx.doi.org/10.1371/journal.pcbi.1007067