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The interaction of several herbal extracts with α-synuclein: Fibril formation and surface plasmon resonance analysis

Proteins from their native conformation convert into highly ordered fibrillar aggregation under particular conditions; that are described as amyloid fibrils. α-Synuclein (α-Syn) is a small natively unfolded protein that its fibrillation is the causative factor of Parkinson’s disease. One important a...

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Detalles Bibliográficos
Autores principales: Honarmand, Shokouh, Dabirmanesh, Bahareh, Amanlou, Massoud, Khajeh, Khosro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559707/
https://www.ncbi.nlm.nih.gov/pubmed/31185031
http://dx.doi.org/10.1371/journal.pone.0217801