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Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility

Maintaining average activity within a set-point range constitutes a fundamental property of central neural circuits. However, whether and how activity set points are regulated remains unknown. Integrating genome-scale metabolic modeling and experimental study of neuronal homeostasis, we identified m...

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Detalles Bibliográficos
Autores principales: Styr, Boaz, Gonen, Nir, Zarhin, Daniel, Ruggiero, Antonella, Atsmon, Refaela, Gazit, Neta, Braun, Gabriella, Frere, Samuel, Vertkin, Irena, Shapira, Ilana, Harel, Michal, Heim, Leore R., Katsenelson, Maxim, Rechnitz, Ohad, Fadila, Saja, Derdikman, Dori, Rubinstein, Moran, Geiger, Tamar, Ruppin, Eytan, Slutsky, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559804/
https://www.ncbi.nlm.nih.gov/pubmed/31047779
http://dx.doi.org/10.1016/j.neuron.2019.03.045