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Glucose controls glucagon secretion by directly modulating cAMP in alpha cells

AIMS/HYPOTHESIS: Glucagon is critical for normal glucose homeostasis and aberrant secretion of the hormone aggravates dysregulated glucose control in diabetes. However, the mechanisms by which glucose controls glucagon secretion from pancreatic alpha cells remain elusive. The aim of this study was t...

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Detalles Bibliográficos
Autores principales: Yu, Qian, Shuai, Hongyan, Ahooghalandari, Parvin, Gylfe, Erik, Tengholm, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560012/
https://www.ncbi.nlm.nih.gov/pubmed/30953108
http://dx.doi.org/10.1007/s00125-019-4857-6