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Central nervous system targeted autoimmunity causes regional atrophy: a 9.4T MRI study of the EAE mouse model of Multiple Sclerosis

Atrophy has become a clinically relevant marker of progressive neurodegeneration in multiple sclerosis (MS). To better understand atrophy, mouse models that feature atrophy along with other aspects of MS are needed. The experimental autoimmune encephalomyelitis (EAE) mouse model of MS was used to de...

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Detalles Bibliográficos
Autores principales: Hamilton, A. Max, Forkert, Nils D., Yang, Runze, Wu, Ying, Rogers, James A., Yong, V. Wee, Dunn, Jeff F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560061/
https://www.ncbi.nlm.nih.gov/pubmed/31186441
http://dx.doi.org/10.1038/s41598-019-44682-6