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Benefits of using genomic insulators flanking transgenes to increase expression and avoid positional effects
For more than 20 years, plant biologists have tried to achieve complete control of transgene expression. Until the techniques to target transgenes to safe harbor sites in the genome become routine, flanking transgenes with genetic insulators, DNA sequences that create independent domains of gene exp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560062/ https://www.ncbi.nlm.nih.gov/pubmed/31186481 http://dx.doi.org/10.1038/s41598-019-44836-6 |