Selective elimination of cancer cells by the adenovirus E4orf4 protein in a Drosophila cancer model: a new paradigm for cancer therapy

The adenovirus (Ad) E4orf4 protein contributes to efficient progression of virus infection. When expressed alone E4orf4 induces p53- and caspase-independent cell-death, which is more effective in cancer cells than in normal cells in tissue culture. Cancer selectivity of E4orf4-induced cell-death may...

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Detalles Bibliográficos
Autores principales: Rosen, Helit, Sharf, Rakefet, Pechkovsky, Antonina, Salzberg, Adi, Kleinberger, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560070/
https://www.ncbi.nlm.nih.gov/pubmed/31186403
http://dx.doi.org/10.1038/s41419-019-1680-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560070/
https://www.ncbi.nlm.nih.gov/pubmed/31186403
http://dx.doi.org/10.1038/s41419-019-1680-4

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