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Neutrophils mediate early cerebral cortical hypoperfusion in a murine model of subarachnoid haemorrhage

Cerebral hypoperfusion in the first hours after subarachnoid haemorrhage (SAH) is a major determinant of poor neurological outcome. However, the underlying pathophysiology is only partly understood. Here we induced neutropenia in C57BL/6N mice by anti-Ly6G antibody injection, induced SAH by endovasc...

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Detalles Bibliográficos
Autores principales: Neulen, Axel, Pantel, Tobias, Kosterhon, Michael, Kramer, Andreas, Kunath, Sascha, Petermeyer, Maximilian, Moosmann, Bernd, Lotz, Johannes, Kantelhardt, Sven R., Ringel, Florian, Thal, Serge C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560094/
https://www.ncbi.nlm.nih.gov/pubmed/31186479
http://dx.doi.org/10.1038/s41598-019-44906-9