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Indoleamine 2,3-dioxygenase and ischemic heart disease: a Mendelian Randomization study
Tryptophan is an essential amino acid. Indoleamine 2,3-dioxygenase (IDO), the rate-limiting enzyme in the tryptophan-kynurenine pathway, is positively associated with cardiac events, and may be relevant to cancer. We used Mendelian Randomization to obtain unconfounded estimates of the association of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560130/ https://www.ncbi.nlm.nih.gov/pubmed/31186442 http://dx.doi.org/10.1038/s41598-019-44819-7 |