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Dual binding mode of “bitter sugars” to their human bitter taste receptor target

The 25 human bitter taste receptors (hTAS2Rs) are responsible for detecting bitter molecules present in food, and they also play several physiological and pathological roles in extraoral compartments. Therefore, understanding their ligand specificity is important both for food research and for pharm...

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Detalles Bibliográficos
Autores principales: Fierro, Fabrizio, Giorgetti, Alejandro, Carloni, Paolo, Meyerhof, Wolfgang, Alfonso-Prieto, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560132/
https://www.ncbi.nlm.nih.gov/pubmed/31186454
http://dx.doi.org/10.1038/s41598-019-44805-z