Cargando…

The Glp-1 Analog Liraglutide Protects Against Angiotensin II and Pressure Overload-Induced Cardiac Hypertrophy via PI3K/Akt1 and AMPKa Signaling

The Glp-1 analog, liraglutide (Lir), has been shown to reduce infarct size and improve cardiac function after myocardial ischemia in rodents with or without diabetes. However, the effect of Lir on angiotensin II (AngII) and pressure overload induced cardiac hypertrophy in nondiabetic mice and the un...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ran, Shan, Yingguang, Gao, Lu, Wang, Xi, Wang, Xule, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560159/
https://www.ncbi.nlm.nih.gov/pubmed/31231210
http://dx.doi.org/10.3389/fphar.2019.00537