Sphingosine kinase 2 inhibitor ABC294640 displays anti-epithelial ovarian cancer activities in vitro and in vivo

Background: ABC294640 is a non-lipid competitive inhibitor of SphK2. It exhibited anti-proliferative activities in many human malignancies, including ovarian cancer. However, its potential mechanism of action remains poorly understood. Methods: In this paper, epithelial ovarian cancer (EOC) cell lin...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Keqi, Dai, Lan, Long, Xiaoran, Cui, Xiaojuan, Liu, Yixuan, Di, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560197/
https://www.ncbi.nlm.nih.gov/pubmed/31239712
http://dx.doi.org/10.2147/OTT.S208519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560197/
https://www.ncbi.nlm.nih.gov/pubmed/31239712
http://dx.doi.org/10.2147/OTT.S208519

Ejemplares similares