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Sphingosine kinase 2 inhibitor ABC294640 displays anti-epithelial ovarian cancer activities in vitro and in vivo
Background: ABC294640 is a non-lipid competitive inhibitor of SphK2. It exhibited anti-proliferative activities in many human malignancies, including ovarian cancer. However, its potential mechanism of action remains poorly understood. Methods: In this paper, epithelial ovarian cancer (EOC) cell lin...
Autores principales: | Song, Keqi, Dai, Lan, Long, Xiaoran, Cui, Xiaojuan, Liu, Yixuan, Di, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560197/ https://www.ncbi.nlm.nih.gov/pubmed/31239712 http://dx.doi.org/10.2147/OTT.S208519 |
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