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Norcantharidin inhibits the DDR of bladder cancer stem-like cells through cdc6 degradation

Introduction: Cancer stem cells (CSCs) are the main source of tumor resistance and recurrence. At present, the main treatment for patients with advanced or metastatic bladder cancer (BCa) is cisplatin-based combination chemotherapy. However, CSCs are not sensitive to DNA-damaging drugs due to their...

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Detalles Bibliográficos
Autores principales: Shi, Xianghua, Chen, Sansan, Zhang, Yongjun, Xie, Weiwei, Hu, Zhiming, Li, Hongwei, Li, Jinlong, Zhou, Zhongxin, Tan, Wanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560209/
https://www.ncbi.nlm.nih.gov/pubmed/31239709
http://dx.doi.org/10.2147/OTT.S209907