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Gephyrin suppresses lung squamous cell carcinoma development by reducing mTOR pathway activation

Background: The mTOR pathway is altered in a multitude of cancers, including lung cancer; however, abnormal activation in this pathway is less common in lung adenocarcinoma (LUAD) than in lung squamous cell carcinoma (LUSC). Gephyrin is a highly conserved and widely expressed ancient protein in vert...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang, Cheng, Dezhi, Liu, Yu, Wu, Yuanbo, He, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560210/
https://www.ncbi.nlm.nih.gov/pubmed/31239782
http://dx.doi.org/10.2147/CMAR.S204358