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Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313

Background: Salmonella Typhimurium ST313 exhibits signatures of adaptation to invasive human infection, including higher resistance to humoral immune responses than gastrointestinal isolates. Full resistance to antibody-mediated complement killing (serum resistance) among nontyphoidal Salmonellae is...

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Detalles Bibliográficos
Autores principales: Ondari, Edna M., Klemm, Elizabeth J., Msefula, Chisomo L., El Ghany, Moataz Abd, Heath, Jennifer N., Pickard, Derek J., Barquist, Lars, Dougan, Gordon, Kingsley, Robert A., MacLennan, Calman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560496/
https://www.ncbi.nlm.nih.gov/pubmed/31231691
http://dx.doi.org/10.12688/wellcomeopenres.15059.1