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The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review
FAK is a tyrosine kinase overexpressed in cancer cells and plays an important role in the progression of tumors to a malignant phenotype. Except for its typical role as a cytoplasmic kinase downstream of integrin and growth factor receptor signaling, related studies have shown new aspects of the rol...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560741/ https://www.ncbi.nlm.nih.gov/pubmed/31186061 http://dx.doi.org/10.1186/s13046-019-1265-1 |