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The expression of NOD2, NLRP3 and NLRC5 and renal injury in anti-neutrophil cytoplasmic antibody-associated vasculitis

BACKGROUND: Nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) are intracellular sensors of pathogens and molecules from damaged cells to regulate the inflammatory response in the innate immune system. Emerging evidences suggested a potential role of NLRs in anti-neutrophil cytopl...

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Detalles Bibliográficos
Autores principales: Wang, Luo-Yi, Sun, Xiao-Jing, Chen, Min, Zhao, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560890/
https://www.ncbi.nlm.nih.gov/pubmed/31186034
http://dx.doi.org/10.1186/s12967-019-1949-5