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Genomic Identification of the TOR Signaling Pathway as a Target of the Plant Alkaloid Antofine in the Phytopathogen Fusarium graminearum

Antofine, a phenanthroindolizidine alkaloid, is a bioactive natural product isolated from milkweeds that exhibits numerous biological activities, including anticancer, antimicrobial, antiviral, and anti-inflammatory properties. However, the direct targets and mode of action of antofine have not been...

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Detalles Bibliográficos
Autores principales: Mogg, Christopher, Bonner, Christopher, Wang, Li, Schernthaner, Johann, Smith, Myron, Desveaux, Darrell, Subramaniam, Rajagopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561021/
https://www.ncbi.nlm.nih.gov/pubmed/31186319
http://dx.doi.org/10.1128/mBio.00792-19