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Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression

While it has been known for several years that viral RNAs are subject to the addition of several distinct covalent modifications to individual nucleotides, collectively referred to as epitranscriptomic modifications, the effect of these editing events on viral gene expression has been controversial....

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Detalles Bibliográficos
Autores principales: Courtney, David G., Chalem, Andrea, Bogerd, Hal P., Law, Brittany A., Kennedy, Edward M., Holley, Christopher L., Cullen, Bryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561033/
https://www.ncbi.nlm.nih.gov/pubmed/31186331
http://dx.doi.org/10.1128/mBio.01209-19