Loganin Attenuates Osteoarthritis in Rats by Inhibiting IL-1β-Induced Catabolism and Apoptosis in Chondrocytes Via Regulation of Phosphatidylinositol 3-Kinases (PI3K)/Akt

BACKGROUND: Chondrocyte apoptosis and catabolism are 2 major factors that contribute to the progression of osteoarthritis (OA). Loganin, an iridoid glycoside present in several herbs, including Flos lonicerae, Cornus mas L, and Strychnos nux vomica, is a valuable medication with anti-inflammatory an...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Gu, Yuntao, Zhao, Hai, Zhang, Shunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561138/
https://www.ncbi.nlm.nih.gov/pubmed/31162482
http://dx.doi.org/10.12659/MSM.915064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561138/
https://www.ncbi.nlm.nih.gov/pubmed/31162482
http://dx.doi.org/10.12659/MSM.915064

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