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Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle

We integrate comeasured gene expression and DNA methylation (DNAme) in 265 human skeletal muscle biopsies from the FUSION study with >7 million genetic variants and eight physiological traits: height, waist, weight, waist–hip ratio, body mass index, fasting serum insulin, fasting plasma glucose,...

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Bibliografische gegevens
Hoofdauteurs: Taylor, D. Leland, Jackson, Anne U., Narisu, Narisu, Hemani, Gibran, Erdos, Michael R., Chines, Peter S., Swift, Amy, Idol, Jackie, Didion, John P., Welch, Ryan P., Kinnunen, Leena, Saramies, Jouko, Lakka, Timo A., Laakso, Markku, Tuomilehto, Jaakko, Parker, Stephen C. J., Koistinen, Heikki A., Davey Smith, George, Boehnke, Michael, Scott, Laura J., Birney, Ewan, Collins, Francis S.
Formaat: Online Artikel Texto
Taal:English
Gepubliceerd in: National Academy of Sciences 2019
Onderwerpen:
Online toegang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561151/
https://www.ncbi.nlm.nih.gov/pubmed/31076557
http://dx.doi.org/10.1073/pnas.1814263116