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Suppressor screening reveals common kleisin–hinge interaction in condensin and cohesin, but different modes of regulation

Cohesin and condensin play fundamental roles in sister chromatid cohesion and chromosome segregation, respectively. Both consist of heterodimeric structural maintenance of chromosomes (SMC) subunits, which possess a head (containing ATPase) and a hinge, intervened by long coiled coils. Non-SMC subun...

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Detalles Bibliográficos
Autores principales: Xu, Xingya, Yanagida, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561158/
https://www.ncbi.nlm.nih.gov/pubmed/31072933
http://dx.doi.org/10.1073/pnas.1902699116